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2016a). This scaled-down raise was proportionate to your lesser peak of PEA levels detected in human volunteers in comparison with beagle puppies. This change, subsequently, could be due to the reduce overall volume of PEA acutely administered to human volunteers (about ?5 vs. 30 mg·kg?one in dogs) and also to The reality that this was a microniz

With this overview, we focus on the molecular targets of PEA, its pharmacological activity in neurological Diseases, suffering perception and inflammatory conditions, plus the present evidence about the usefulness of micronized and extremely?micronized formulations of PEA when presented by yourself or together Together with the antioxidant flavonoi